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Mathilde Boissel

Contact Info

Computer Skills

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Last updated on novembre. 2019.

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Mathilde Boissel

Curriculum Vitæ

With a master’s degree in Applied Mathematics and Statistics, I like projects with mental challenges, precision and team work. I have skills in programming and statistical methods, with a solid educational foundation and a passion for science.

Professional & Research Experience

Biostatistician Engineer

UMR8199 - University of Lille

Lille, France

10/2018 - Today

Activities: Genomic studies in the diabetes and obesity field

  • GWAS, EWAS, eQTL, mQTL, DE analyses, Rare variant analyses (burden and dispersion test)
  • Statistical modelling, Clustering methods, Methodological support
  • DNA microarray, Methylation chip and Next-Generation Sequencing
  • Use of various DB : 1000 genomes, Ensembl, dbNSFP, COSMIC, DAVID
  • Involved in several CONSORTIUM (CHARGE, CKDGen, IMIDIA)

Biostatistician Engineer

UMR8199 - CNRS

Lille, France

10/2015 - 10/2018

Activities: Genomic studies in the diabetes and obesity field

Intern Modelling a treatment decision-making support

Centre de Traitement des Données - CNO

Caen, France

04/2015 - 09/2015

Activities: Modelling a recommendation system, applied for Hodgkin’s lymphoma patients

  • Model combinating survival probabilities and patient ratings on their quality of life and iatrogenic effects, tested by simulation
  • Interactive decision-making support (developped with Drupal, WAMP, HTML, PHP and JS)
  • Introduction to data managment (Clinsight eCRF and CDISC)

Fixed term contract Project VegeDurable 2

Université de Caen

Caen, France

01/2014 - 04/2014

Activities: Research of the effects of fertilizers, density of soil and water concentration in carrot production

  • Statistical modelling and clustering of measures taken in the carrot plot

Intern Estimating of the convolution kernel of the hemodynamic response for the treatment of fMRI data

Cyceron - Site GANIL

Caen, France

05/2014 - 06/2014

Activities: Estimation of parameters of hemodynamic response function

  • Introduction to treatment of fMRI data (with R and Matlab), BOLD signal, software SPM, ImageJ

Intern –volontary- Methodologist

Lab COMETE - INSERM - CHU

Caen, France

06/2013 - 06/2013

Activities: Analysis with R and SAS of data about hypovigilance on roads

Education

Master Degree of Science (M. Sc), in Applied Mathematics “MASS”

University of Caen

Caen, France

2013 - 2015

Speciality: Decision support in business

  • Statistics (R, SAS, VBA Excel)
  • Computer science (POO Python, MySQL, HTML5, CSS3)
  • Mathematics of the decision
  • Economic and social sciences (Macro and Micro, Management control, Marketing, Optimization, Supply chain, Project management)

Bachelor Degree of Science (B. Sc), in Applied Mathematics “MASS”

University of Caen

Caen, France

2010 - 2013

Broad-spectrum of knowledge theoretical and practical subjects as statistics, computing, economy, survey and polls, marketing, econometrics, bio-statistics, management control, logistic management…

Scientific Baccalauréat, Speciality: Mathematics

Lycée Le Verrier

Saint-Lô, France

2007 - 2010

Packages

CARoT: Centralised and Automated RepOrting Tools

mcanouil, mboissel and Ning-L

GitHub

juil.. 2019

https://github.com/mboissel/CARoT/

CRAN_Status_Badge

Oral/Poster communications

Feedback on RNA-seq data analyses

Journal Club - UMR8199

Lille, France

28/05/2018

Slides

Analyse de variants rares issus de données de séquençage à haut débit

Working group RIS Statistics and Genomics

Paris, France

12/10/2018

Slides

Shiny Web application framework for R

Min2Rien

Lille, France

04/04/2017

Slides
Video

Major publications (2/9)

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension

Morgane Baron, Julie Maillet, …, Mathilde Boissel26 et al.

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Nov. 2019

Nature Medicine

Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling

Angeliki Karamitri, Bianca Plouffe, …, Mathilde Boissel8 et al.

N/A

NA 2018

Science Signaling

INTEREST

Sports

Martial art (2y Karaté, 2y Jujitsu, 6y Judo), sports needing rigor, respect and humility

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Trips

European big Cities, Moto bike, Hike

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Scientific events

Steering committee in a UseR group under construction at Lille; Steering committee in the CNRS working group RIS Statistics and Genomics; “Fête De la Scièce” at Lille;

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RIS;
Fête De la Science;

Languages

English (professional, Certification C.L.E.S), French (Mother tongue)

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